Process Systems Engineer for Model Based Design

Indrykket: 23.7.2020

Novo Nordisk, Bagsværd

  • Research
  • Bagsværd

Do you want to contribute to building our process modelling function in R&D and set your mark on how we optimize production processes for the future? Then you could be our new Process Systems Engineer for design and optimization.

About the department

The job is placed in CMC API Development, R&D, located in Bagsværd. Our main responsibility is to develop manufacturing processes for new proteins and peptides in close collaboration with the research and manufacturing units (clinical and market). In CMC API Development we are increasing our focus on improving emerging processes by application of flow sheet models (Digital Twins). The Digital Twin combines a model for a facility with a process model and enables us to optimize for different objectives throughout the project lifecycle, including capacity, facility fit, and process economy. The Digital Twin is based on a dynamic mass balance for the entire system and production scenarios are simulated by solving the system of equations using Discrete Event Simulation. For selected process steps mechanistic models are included to increase model fidelity. Our aim for the future is to enable more qualified and timely decisions on process design such as batch vs continuous operation, solvent prep strategy, and recycle options.

You will be part of a small team, CMC Bioprocess Improvement-Optimization (CMC BIO), which is dedicated to model based process design, in close collaboration with Upstream & Downstream departments. Similar teams are found in our Production and Pilot areas as part of a growing modelling network.

The job

As part of CMC BIO you will:

  • design and optimize emerging processes in collaboration with project stake holders
  • develop and improve a methodology for process design
  • build and maintain facility models in collaboration with Production and Pilot areas
  • establish the Digital Twin concept as a tool for designing new facilities

This job gives you a great opportunity to play a part in shaping the future of bioprocessing in close collaboration with development, production, and research teams in Novo Nordisk.


You have a PhD in chemical engineering with focus on Process Systems Engineering, design and optimization. Good programming skills and a talent for handling software and data. Experience within (bio)chemical processes and Discrete Event Simulation.

You are able to:

  • develop simulation models from high level descriptions of entire facilities to detailed analysis of utility/solvent systems
  • use tools like INOSIM, SuperPro, PRO/II, GAMS and program in VBA, MatLab, Python, C++
  • apply simplified and complex models in the right proportions to balance speed and accuracy
  • capture the essence of an assignment and break it down into manageable pieces
  • present complex results in a clear way and explain the purpose to get everyone onboard

For further information, please contact Scientific Director Ernst Broberg Hansen at +45 3079 7809

12 Aug 2020.

Applications are reviewed ongoing

Millions rely on us
To work for Novo Nordisk you will need the skills, dedication and ambition to change lives for the better for millions of patients living with diabetes and other chronical diseases. In exchange, we offer the chance to be part of a truly global workplace, where passion and engagement are met with opportunities for professional and personal development.
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At Novo Nordisk, we are driving change to defeat diabetes and other serious chronic diseases.

Novo Nordisk is a global healthcare company with more than 95 years of innovation and leadership in diabetes care. This heritage has given us experience and capabilities that also enable us to help people defeat other serious chronic diseases: haemophilia, growth disorders and obesity.

Headquartered in Denmark, Novo Nordisk employs approximately 43,200 people in 80 countries and markets its products in more than 170 countries.