PhD fellowship in acute stroke in postmenopausal women
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The Department of Nutrition, Exercise and Sports (NEXS), section for Human Physiology, invites applicants for a PhD fellowship in “Noncoding RNAs, the Epitranscriptome and the Epigenome as Effectors of Physical Activity in Lowering the Risk of Acute Stroke in Postmenopausal Women.”
Start date is 1 March 2024 or as soon as possible thereafter.
The project
Acute stroke is a leading cause of disability and death, affecting over 1 million people per year in Europe alone. Physical activity is the most effective way to reduce the risk of all cardiovascular events, including stroke. However, after menopause, a transition where the risk of severe cardiovascular events increases drastically for women, the effects of physical activity on the vascular system can change. The molecular pathways underlying these important changes are not yet understood.
To elucidate these pathways, you will look specifically at noncoding RNAs. RNAs respond rapidly to stimuli such as physical activity and can travel and communicate between different tissues, such as between skeletal muscles and the brain. Furthermore, in response to such stimuli, RNAs undergo chemical modifications at individual nucleotide level, adapting the distinct biological functions of these RNAs. You will combine studies on acute stroke in women and studies in women of varying physical activity/fitness levels going through menopausal transition, with in vitro studies on primary human brain endothelial cells to elucidate underlying cellular RNA signalling pathways.
Who are we looking for?
We are looking for candidates within the field of human physiology. Applicants can have a background in human physiology, exercise physiology or similar.
Our group and research- and what do we offer?
The group is a part of the section for Human Physiology at the Department of Nutrition, Exercise and Sports (NEXS), Faculty of SCIENCE, University of Copenhagen. We are located in Copenhagen.
We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and exercise facilities.
Further information on the Department is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/ and https://nexs.ku.dk/english/research/the-august-krogh-section-for-human-physiology/.
Principal supervisor isDr. A.Y. Nossent, [email protected].
The PhD programme is a three year full-time study within the framework of the regular PhD programme; you already have an education equivalent to a relevant Danish master’s degree.
Qualifications needed for the regular programme
To be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. Human Physiology. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database.
Terms of employment in the regular programme
Employment as PhD fellow is full time and for maximum 3 years.
Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.
Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.
Responsibilities and tasks in the PhD programme
We are looking for the following qualifications:
Application and Assessment Procedure
Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.
Please include:
Application deadline:
The deadline for applications is Friday 22 December 2023, 23:59 GMT+1.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.
The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
Interviews with selected candidates are expected to be held in week 3+4 January 2024.
Questions
For specific information about the PhD fellowship, please contact the principal supervisor.
General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://www.science.ku.dk/phd/.
The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Start date is 1 March 2024 or as soon as possible thereafter.
The project
Acute stroke is a leading cause of disability and death, affecting over 1 million people per year in Europe alone. Physical activity is the most effective way to reduce the risk of all cardiovascular events, including stroke. However, after menopause, a transition where the risk of severe cardiovascular events increases drastically for women, the effects of physical activity on the vascular system can change. The molecular pathways underlying these important changes are not yet understood.
To elucidate these pathways, you will look specifically at noncoding RNAs. RNAs respond rapidly to stimuli such as physical activity and can travel and communicate between different tissues, such as between skeletal muscles and the brain. Furthermore, in response to such stimuli, RNAs undergo chemical modifications at individual nucleotide level, adapting the distinct biological functions of these RNAs. You will combine studies on acute stroke in women and studies in women of varying physical activity/fitness levels going through menopausal transition, with in vitro studies on primary human brain endothelial cells to elucidate underlying cellular RNA signalling pathways.
Who are we looking for?
We are looking for candidates within the field of human physiology. Applicants can have a background in human physiology, exercise physiology or similar.
Our group and research- and what do we offer?
The group is a part of the section for Human Physiology at the Department of Nutrition, Exercise and Sports (NEXS), Faculty of SCIENCE, University of Copenhagen. We are located in Copenhagen.
We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and exercise facilities.
Further information on the Department is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/ and https://nexs.ku.dk/english/research/the-august-krogh-section-for-human-physiology/.
Principal supervisor isDr. A.Y. Nossent, [email protected].
The PhD programme is a three year full-time study within the framework of the regular PhD programme; you already have an education equivalent to a relevant Danish master’s degree.
Qualifications needed for the regular programme
To be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. Human Physiology. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database.
Terms of employment in the regular programme
Employment as PhD fellow is full time and for maximum 3 years.
Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.
Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.
Responsibilities and tasks in the PhD programme
- Carry through an independent research project under supervision
- Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE
- Participate in active research environments, including a stay at another research institution, preferably abroad
- Teaching and knowledge dissemination activities
- Write scientific papers aimed at high-impact journals
- Write and defend a PhD thesis on the basis of your project
We are looking for the following qualifications:
- Professional qualifications relevant to the PhD project
- A relevant publication in the field of exercise physiology
- Relevant work experience with human subjects in a cardiovascular context
- Good skills in wet-lab analysis
- Other relevant professional activities
- Curious mind-set with a strong interest in exercise physiology, female hormone signaling, cardiovascular disease and RNA biology
- Good language skills in written and spoken Danish and English
Application and Assessment Procedure
Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.
Please include:
- Your motivation for applying for the specific PhD project
- Curriculum vitae including information about your education, experience, language skills and other skills relevant for the position
- Original diplomas for Bachelor of Science or Master of Science and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
- Publication list (if possible)
- Reference letters (if available)
Application deadline:
The deadline for applications is Friday 22 December 2023, 23:59 GMT+1.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.
The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
Interviews with selected candidates are expected to be held in week 3+4 January 2024.
Questions
For specific information about the PhD fellowship, please contact the principal supervisor.
General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://www.science.ku.dk/phd/.
The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Øvrige", og befinder sig i kategorien "Øvrige stillinger".
Arbejdsstedet er beliggende i København N.
Jobbet er oprettet på vores service den 28.11.2023, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Øvrige
- København N
- Fredag den 22. december 2023
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