Principal Quantitative Systems Pharmacology Scientist

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Are you looking for an exciting opportunity to use your experience within Quantitative Systems Pharmacology (QSP)? We are looking for a principal scientist with advanced mathematical modelling skills and a strong understanding of Systems Biology/Pharmacology to join our QSP team in a permanent position within the Novo Nordisk Research and Early Development organization. The position As a Principal QSP Scientist, you will be involved in a variety of projects and therapeutic areas incorporating QSP. You will be working in interdisciplinary teams, with a focus to support and integrate in vitro and in vivo pharmacology data into current or new QSP models to describe the dynamic interactions between drug(s) and biological systems, in order to inform and support drug discovery, development and regulatory interactions. You will be mentoring colleagues within the department and ensure high quality QSP modelling approaches and expert knowledge within the QSP field. The successful candidate will work in a small intradepartmental team, which collectively, will drive the implementation of QSP and liaise with scientists across the R&D organisation. The work will include expanding internal QSP capabilities, as well as collaborating with external partners. In addition to strong skills within mathematical modelling and biology, the work will also require strong collaboration and communication skills to coordinate input from experts from different scientific areas. Qualifications You hold Ph.D. in Physics, Math, Engineering or other disciplines related to quantitative biology/pharmacology or equivalent experience with a strong emphasis on pharmacological modelling and simulation is required. You have 5-8 years of relevant pharmaceutical industry experience within R&D.To succeed in the role, you have:
  • Excellent understanding of theory, principles and statistical aspects of advanced mathematical modelling and simulation
  • Expertise with Quantitative Systems Pharmacology (QSP) is required
  • Proficiency and programming skills with modelling or analytical software (e.g., PK-Sim, R, Matlab/SimBiology, Python)
  • Understanding of pharmacokinetics and modelling software (i.e., Phoenix WinNonlin/NLME or equivalent) with Physiologically Based Pharmacokinetics (PBPK) software is preferred
  • Ability and interest to learn new areas of biological sciences
  • Excellent oral and written language communication skills. Business is conducted using English
  • Excellent team player and communicator and ability to effectively interact with colleagues with a variety of backgrounds
  • About the department The QSP activities are anchored in the DMPK area. The area supports the discovery and development portfolio with pharmacokinetic (PK) and pharmacodynamic (PD) evaluations using a variety of modelling and simulation tools. QSP is an important part of our capabilities within mechanistic modelling. You will have highly skilled and dedicated colleagues supporting projects from early discovery, through non-clinical development, as well as early clinical development. Within the overall Novo Nordisk organization, the department is anchored within Research & Early Development. In our daily work, we have close collaboration with all parts of the global Discovery and Development organisation, research project teams as well as external collaborators. Working at Novo Nordisk At Novo Nordisk, we don’t wait for change. We drive it. We’re a dynamic company in an even more dynamic industry, and we know that what got us to where we are today is not necessarily what will make us successful in the future. We embrace the spirit of experimentation, striving for excellence without fixating on perfection. We never shy away from opportunities to develop, we seize them. From research and development to manufacturing, marketing and sales – we’re all working to move the needle on patient care. Contact
    For further information, please contact the Director of Discovery & Development PKPD, Charlotte Keller Steensberg at +45 3079 1641. Deadline
    10 March 2023. Please note that applications will be assessed on an ongoing basis and therefore the advert may close before the recruitment process is completed if we have proceeded with candidates to the screening or interview phase. To ensure an efficient and fair recruitment process, please refrain from adding a photo in your CV. We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.


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    Denne ledige stilling har jobtypen "Forretningsudvikler", og befinder sig i kategorien "Kommunikation, marketing, salg".

    Arbejdsstedet er beliggende i Måløv.

    Jobbet er oprettet på vores service den 2.2.2023, men kan have været deaktiveret og genaktiveret igen.

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